Documentation Status PyPI License

MAmotif is an integrative toolkit for searching cell type-specific co-factors associated with differential binding.


  • Quantitatively compare ChIP-Seq samples by robust linear regression on common protein binding sites(peaks) (MAnorm model)

  • Scan for motif target sites and perform motif enrichment analysis on genomic regions

  • Identify transcriptional factors (TFs) associated with the cell-type differential binding

  • Search for candidate cell-type specific regulators