MAmotif is an integrative toolkit for searching cell type-specific co-factors associated with differential binding.
Quantitatively compare ChIP-Seq samples by robust linear regression on common protein binding sites(peaks) (MAnorm model)
Scan for motif target sites and perform motif enrichment analysis on genomic regions
Identify transcriptional factors (TFs) associated with the cell-type differential binding
Search for candidate cell-type specific regulators
The Python version of MAmotif is developed by ShaoLab at CAS-MPG Partner Institute for Computational Biology, SIBS, CAS.
GitHub repository of MAmotif: https://github.com/shao-lab/MAmotif